News and Views from Industry: Crossing the BBB, the Brain Shuttle design


The Brain Shuttle

Researchers at the Hoffmann-La Roche institute of Basel have developed a transferrin receptor-based system, the Brain Shuttle, to increase the BBB penetration of an Ab-specific antibody into the brain of a mouse model for Alzheimer’s disease.

On a broader range of application, the Brain Shuttle might be designed for the transport of a variety of molecules across the BBB, such as therapeutic growth factors, enzymes and peptides.

The Brain Shuttle experiment, published in the January 8 Neuron, will be presented by Dr. Ludovic Collin, senior scientist at Basel Hoffmann-La Roche Ltd. and co-author of the study.


Donnerstag, 12. Juni 2014 - 14:30


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